| Nick Bonino | 47 | Torn Left ACL Injury | 53 day(s) |
| Jake DeBrusk | 47 | Bruised Right Shoulder Injury | 53 day(s) |
| Michael Kesselring | 69 | Fractured Bone in Left Hand Injury | 31 day(s) |
| Stefan Noesen | 77 | Left Forearm Injury | 23 day(s) |
| Boone Jenner | 77 | Broken Left Thumb Injury | 23 day(s) |
| Logan Cooley | 79 | Sprained Left Ankle Injury | 21 day(s) |
| Steven Stamkos | 81 | Abdominal Strain Injury | 19 day(s) |
| Casey DeSmith | 81 | Right Eye Injury | 19 day(s) |
| Brendan Gallagher | 83 | Bruised Right Arm Injury | 17 day(s) |
| Scott Wedgewood | 87 | Left Leg Injury | 13 day(s) |
| Pierre-Edouard Bellemare | 90 | Broken Bone (Left Ankle) Injury | 10 day(s) |
| Cole Perfetti | 92 | Left Hand Injury | 8 day(s) |
| Trent Frederic | 92 | Right Hand Injury | 8 day(s) |
| Nick Paul | 93 | Left Leg Injury | 7 day(s) |
| Carson Soucy | 93 | Strained Left Elbow Injury | 7 day(s) |
| Jet Greaves | 93 | Exhaustion | 7 day(s) |
| Sam Carrick | 93 | Left Foot Injury | 7 day(s) |
